Comparative Genomics, Development, Physiology and Systematics of the Brassicaceae and Cleomaceae
Lysak, Martin A. .
Evolutionary and comparative cytogenetics of the Brassicaceae and Cleomaceae.
The availability of chromosome-specific libraries of large-insert (BAC) clones of Arabidopsis thaliana has fuelled the unparalleled boom of comparative molecular cytogenetics in the family Brassicaceae. The past seven years were characterized by Arabidopsis-centered comparative cytogenetics leading to some unprecedented discoveries. Comparative chromosome painting using Arabidopsis BAC contigs combined with comparative genetic mapping were used to (i) identify the level of chromosome colinearity across Brassicaceae, (ii) reconstruct evolutionary scenarios of karyotype evolution in species with varying chromosome number (n=5-8), (iii) unearth the paleopolyploid history of some crucifer lineages, and (iv) establish a tentative Ancestral Karyotype (AK; n=8) for Brassicaceae. Within the Ancestral Karyotype, conserved chromosomal building blocks can be reshuffled to model the genome structure of various crucifer species. Now the most challenging objectives of comparative phylogenomics in Brassicaceae are the identification of the ancestral building blocks and reconstruction of karyotype evolution in different phylogenetic lineages within the family. Moving away from Arabidopsis-centered comparative phylogenomics, the genus Aethionema and the family Cleomaceae are now receiving special attention being repeatedly found to be sister to the remaining crucifer taxa and Brassicaceae, respectively. However, such comparisons are hampered by the fact that most of Aethionema and Cleomaceae species are polyploid. To initiate comparative cytogenetics across Brassicales, a quest for “model” diploid (n=8) Aethionema and Cleome species is now being undertaken.
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1 - Masaryk University, Department of Functional Genomics and Proteomics, Kamenice 5, Building A2, Brno, 62500, Czech Republic
Presentation Type: Symposium or Colloquium Presentation
Location: Stevens 2/Hilton
Date: Monday, July 9th, 2007
Time: 4:00 PM