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Abstract Detail


A Historical Perspective on Chicago Area Botany

Shapiro, James [1].

Barbara McClintock, a 21st Century Biologist.

Barbara McClintock was a pioneer in the new science of genetics throughout most of the 20th Century. In addition to her pioneering cytogenetic work on the correspondence between chromosome structure and genetic linkage groups, organization of chromosomes into distinct functional domains, and repair of chromosome breakage, she received the 1983 Nobel Prize for discovering mobile genetic elements. McClintock’s penetrating observations on the cellular control of genome function and genome restructuring remain less widely appreciated. By integrating her intimate knowledge of plant biology with an organic vision of how the genome operates in development and evolution, McClintock anticipated the revolution from mechanics to informatics as the core of 21st Century biology.


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Related Links:
Barbara McClintock autobiography
McClintock papers
Nobel Prize address


1 - University of Chicago, Biochemistry and Molecular Biology, Gordon Center for Integrative Science, 929 E. 57th Street, Chicago, IL, 60637, USA

Keywords:
mobile genetic elements
genome restructuring
cellular control
informatics.

Presentation Type: Symposium or Colloquium Presentation
Session: SY12
Location: Williford C/Hilton
Date: Tuesday, July 10th, 2007
Time: 11:00 AM
Number: SY12007
Abstract ID:587


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