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Abstract Detail


Large Scale Technologies and Resources

Farag, Mohamed A. [1], Broeckling, Corey D. [2], Huhman, David V. [3], Urbanczyk-Wochniak, Ewa [3], Lei, Zhentian [3], Nagaraj, Satish [3], Watson, Bonnie S. [3], Naoumkina, Marina [3], Deavours, Bettina [3], Dixon, R. A. [3], Sumner, Lloyd W. [4].

Integrated Functional Genomic Studies of Biotic Stress Responses in the Model Legume Medicago truncatula.

Legumes are critical to world agricultural economics, and to human and animal nutrition. Medicago truncatula is a rapidly maturing model for the study of legume biology, and is an excellent species for fundamental studies of secondary metabolism (Dixon and Sumner, 2003). An integrated functional genomics project that is studying the response of Medicago truncatula to biotic and abiotic stress is underway and includes the large-scale analyses of mRNA, proteins, and metabolites. This presentation will focus on the proteomics and metabolomics aspects of this project within the overall context of an integrated functional genomics approach. Descriptions and rationale will be provided for the technologies being used and a brief discussion will be provided on the critical bioinformatic components of the project. Specific examples will then be presented that illustrate how proteomics and metabolomics are yielding valuable information relative to gene validation, gene discovery, hypothesis building, and enhanced mechanistic understanding.


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Related Links:
project website
Sumner laboratory website


1 - Cairo University, Egypt., Pharmacognosy Department, Faculty of Pharmacy
2 - Colorado State University, Department of Horticulture and Landscape Architecture
3 - The Samuel Roberts Noble Foundation, Plant Biology
4 - The Samuel Roberts Noble Foundation, Plant Biology, PO Box 2180, Ardmore, OK, 73401, USA

Keywords:
Medicago truncatula
Functional genomics
proteomics
metabolomics
biotic stress.

Presentation Type: Plant Biology Abstract
Session: P
Location: Exhibit Hall (Northeast, Southwest & Southeast)/Hilton
Date: Sunday, July 8th, 2007
Time: 8:00 AM
Number: P42002
Abstract ID:356


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