Johnson, Deborah Alongi , Hill, Jeffrey P. , Thomas, Michael A. .
Functional Divergence and Evolution of Expression in the Monosaccharide Transporters of Arabidopsis and Rice.
The recent availability of whole genome sequence data in many taxa across the tree of life has allowed evolutionary biologists to test hypotheses of gene duplicate divergence and constraint on protein sequence evolution. Evidence for the neofunctionalization, subfunctionalization, and subneofunctionalization gene duplicate divergence models have been found. Relationships between rates of sequence evolution and factors such as gene expression level, expression breadth, protein-protein interactions, and protein length have also been observed, although correlations have been weak. In this study, we analyze relationships between gene expression level and breadth with rates of sequence evolution in the monosaccharide transporter (MST) gene families of Arabidopsis and rice. We also explore the evolution of gene expression in three clades of MSTs where large numbers of tandem duplications have greatly expanded MST subfamilies. Results show weak but statistically significant correlations between gene expression level/breadth and rates of sequence evolution. We also see patterns of conserved sequence evolution in genes giving rise to many paralogs, and evidence of partitioning of gene expression among paralogs, consistent with a subfunctionalization model.
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1 - Idaho State University, Biological Sciences, Campus Box 8007, Pocatello, ID, 83209, USA
2 - Idaho State University, Biological Sciences
comparative functional genomics
gene expression level
gene expression evolution
gene expression breadth.
Presentation Type: Plant Biology Abstract
Location: Exhibit Hall (Northeast, Southwest & Southeast)/Hilton
Date: Sunday, July 8th, 2007
Time: 8:00 AM