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Abstract Detail


Epigenetics

Liu, Shiming [1], Yu, Yu [1], Ruan, Ying [1], Xu, Lin [1], Wolff, Michel [1], Meyer, Denise [1], Shen, Wen-Hui [1].

SET- and RING-associated domain proteins bridge histone and DNA methylation.

The heterochromatin of many eukaryotes is marked by both histone H3 lysine 9 (H3K9) methylation and DNA cytosine methylation. Several studies have revealed existing links between these two epigenetic marks. The molecular mechanisms involved in establishment of these links, however, remain largely unknown. We will show molecular and functional characterization of SET- and RING-associated domain proteins, suggesting their roles in bridging histone and DNA methylation.


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1 - IBMP-CNRS, Cell Biology, 12 rue du General Zimmer, Strasbourg, 67084, France

Keywords:
chromatin modification
methylation
epigenetics
histone.

Presentation Type: Plant Biology Abstract
Session: P
Location: Exhibit Hall (Northeast, Southwest & Southeast)/Hilton
Date: Sunday, July 8th, 2007
Time: 8:00 AM
Number: P38007
Abstract ID:2385


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